Efecto de la hesperidina sobre la captación de hdl en células hepáticas y evaluación de hesperidina liposomal sobre la oxidación de ldl
Abstract
La hesperidina es un flavonoide con varios reportes de bioactividad. En el presente trabajo se demostró la potencialidad de tres fuentes vegetales para la obtención industrial de hesperidina, la cual fue probada sobre dos modelos de procesos claves en la patología cardiovascular: la captación de HDL por células hepáticas y la oxidación de LDL. Sin embargo, la hesperidina presenta una utilidad farmacéutica limitada debido a su baja solubilidad en agua, por lo tanto se exploró la alternativa de incorporar hesperidina en liposomas encontrando altos porcentajes de encapsulación y un aumento en la inhibición de LDL comparada con el compuesto libreDownloads
Downloads
-
Vistas(Views): 659
- PDF (Español (España)) Descargas(Downloads): 698
Published
How to Cite
Issue
Section
License
Copyright (c) 2017 Scientia et technica

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
The undersigned authors declare that the article submitted to the journal Scientia et Technica is an original work and that all its content is free of third-party copyright restrictions or has the corresponding authorizations. Consequently, the authors assume responsibility for any litigation or claim related to intellectual property rights, releasing the Technological University of Pereira and the journal Scientia et Technica from any liability.
If the submitted work is accepted for publication, the authors retain copyright to the article and grant the journal Scientia et Technica the right of first publication, as well as a non-exclusive, perpetual license to reproduce, edit, distribute, display, and publicly communicate the article in any medium or format, including print, electronic, databases, repositories, the Internet, or other scientific dissemination systems. The authors agree that the article will be published in open access and distributed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (CC BY-NC-SA 4.0).
The journal Scientia will respect in all cases the moral rights of the authors, in accordance with the provisions of article 30 of Law 23 of 1982 of the Republic of Colombia, recognizing the authorship of the work, the right to integrity and the right of disclosure, which are inalienable and non-waivable.