Actividad ictiotóxica y citotóxica de extractos de plantas Chrysobalanaceae, Melastomataceae, Rubiaceae y Rutaceae, de la flora Colombiana
DOI:
https://doi.org/10.22517/23447214.8375Keywords:
células Vero, citotoxicidad, ictiotoxicidad, Poecilia reticulata.Abstract
Resumen— Se evaluó la actividad ictiotóxica y citotóxica de diez plantas pertenecientes a familias Chrysobalanaceae, Melastomataceae, Rubiaceae y Rutaceae. Se obtuvieron los extractos acuoso y butanólico, los cuales fueron evaluados frente a peces guppy (Poecilia reticulata) y frente a células Vero. El más alto porcentaje de actividad ictiotóxica (%AI) fue presentada por los extractos butanólico y acuoso de Miconia caudata (Bonpl.) DC., Miconia aeruginosa Naud., Miconia sp., Clidemia hirta (L.) D. Don., Palicourea lyristipula Wern L. e Hirtella racemosa Lam. En la prueba de citotoxicidad los extractos de Clidemia hirta y Miconia sp. se presentaron como parcialmente activos; el resto no se mostraron activos frente a células Vero.
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