Platelet distribution width as a marker for the development of severe preeclampsia


Authors

  • Carlos Andres Trejos Ramirez Universidad de la Sabana
  • Fabiana Ramirez Pescador Universidad Santiago de Cali
  • Jorge Augusto Rodriguez Ortiz Hospital Simon Bolivar
  • Mortimer Arreaza Graterol Hospital Simon Bolivar

DOI:

https://doi.org/10.22517/25395203.19011

Keywords:

Toxemia, Pre-eclampsia, blood platelets disorders

Abstract

Introduction: The pathophysiology of preeclampsia is not
completely elucidated. Different platelet indices, including the
platelet distribution width (PDW), could be used to predict the
severity of this condition.
Objective: To analyze the behavior of PDW in the severity
development of preeclampsia in women treated in the
maternal-fetal medicine unit of Hospital Simón Bolívar in
Bogotá, Colombia.
Materials and methods: This is an analytical cross-sectional
study in 105 patients with hypertensive disorder associated
with pregnancy, preeclampsia and severe preeclampsia. We
analyzed the behavior of PDW in a population of hypertensive
women with preeclampsia using a curve of analysis ‘’ Receiver
Operating Characteristic ‘’ (ROC) to estimate the sensitivity,
false positive rate, positive and negative likelihood ratio of the
test as a marker of development of severity
Results: PDW had a higher significant increase in
patients where their disease progression developed severity
characteristics. In the ROC curve, the area under the curve for
PDW as a predictor of severity in preeclampsia was 0.68.
Conclusion: PDW is a platelet index that increased
significantly in women with preeclampsia with severity
characteristics. PDW could be a marker for the prediction of
severity of preeclampsia

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Author Biographies

Carlos Andres Trejos Ramirez, Universidad de la Sabana

Soy residente de ultimo año de G/O, egresado de pregrado de la facultad de medicina de la UTP

Fabiana Ramirez Pescador, Universidad Santiago de Cali

Medico egresado de la universidad Santiago de Cali

Jorge Augusto Rodriguez Ortiz, Hospital Simon Bolivar

Ginecoobstetra, especialista en Epidemiología Clínica, Unidad de Medicina Maternofetal. Hospital Simón Bolívar (Bogotá D.C., Colombia).

Mortimer Arreaza Graterol, Hospital Simon Bolivar

Ginecoobstetra, especialista en Medicina Materno-Fetal, Unidad de Medicina Maternofetal. Hospital Simón Bolívar (Bogotá D.C., Colombia).

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Published

2020-06-12

How to Cite

Trejos Ramirez, C. A., Ramirez Pescador, F., Rodriguez Ortiz, J. A., & Arreaza Graterol, M. (2020). Platelet distribution width as a marker for the development of severe preeclampsia. Revista Médica De Risaralda, 25(2). https://doi.org/10.22517/25395203.19011

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Section

Original Article