Prevalencia de factores etiológicos para deficiencia de vitamina B 12 en una población de Palmira, Valle, Colombia. Estudio retrospectivo de corte transversal.
DOI:
https://doi.org/10.22517/25395203.25622Keywords:
vitamina B 12, anemia, inhidores de bombas de protones, metformina, hipotiroidismoAbstract
Introduction: vitamin B 12 deficiency is a clinical condition with multiple causes. Its main clinical manifestations are hematological and neuropsychiatric.
Objectives: to establish the sociodemographic characteristics and the prevalence of etiological factors for vitamin B 12 deficiency in a population of Palmira, Colombia.
Materials and methods. A retrospective cross-sectional study was developed in a tertiary referral center in Palmira, Colombia. The study period was from March 1, 2020, to March 1, 2023. Electronic medical records were reviewed to obtain information on patients' clinical characteristics, comorbidities, and laboratory tests.
Results and conclusions. Vitamin B 12 deficiency mainly affects the adult population and the elderly. Among the etiological factors, autoimmune diseases (mainly primary hypothyroidism due to Hashimoto's thyroiditis) and the consumption of some medications such as metformin and proton pump inhibitors stood out with greater prevalence.
Downloads
References
Stabler SP. Clinical practice. Vitamin B12 deficiency. N Engl J Med. 2013;368(2):149-60.
Green R, Allen LH, Bjorke-Monsen AL, Brito A, Gueant JL, Miller JW, et al. Vitamin B(12) deficiency. Nat Rev Dis Primers. 2017;3:17040.
Green R. Vitamin B(12) deficiency from the perspective of a practicing hematologist. Blood. 2017;129(19):2603-11.
Silverstein WK, Cheung MC, Lin Y. Vitamin B(12) deficiency. CMAJ. 2022;194(24):E843.
Candelario N, Klein C. Megaloblastic anemia due to severe vitamin B(12) deficiency. Cleve Clin J Med. 2022;89(1):8-9.
Htut TW, Thein KZ, Oo TH. Pernicious anemia: Pathophysiology and diagnostic difficulties. J Evid Based Med. 2021;14(2):161-9.
Rashid S, Meier V, Patrick H. Review of Vitamin B12 deficiency in pregnancy: a diagnosis not to miss as veganism and vegetarianism become more prevalent. Eur J Haematol. 2021;106(4):450-5.
Collins AB, Pawlak R. Prevalence of vitamin B-12 deficiency among patients with thyroid dysfunction. Asia Pac J Clin Nutr. 2016;25(2):221-6.
Linder L, Tamboue C, Clements JN. Drug-Induced Vitamin B(12) Deficiency: A Focus on Proton Pump Inhibitors and Histamine-2 Antagonists. J Pharm Pract. 2017;30(6):639-42.
Kesbeh Y, Pakbaz Z. Pernicious anemia: a myelodysplastic syndrome look-alike. J Community Hosp Intern Med Perspect. 2019;9(3):240-3.
Irvine WJ, Davies SH, Teitelbaum S, Delamore IW, Williams AW. The clinical and pathological significance of gastric parietal cell antibody. Ann N Y Acad Sci. 1965;124(2):657-91.
Bell DSH. Metformin-induced vitamin B12 deficiency can cause or worsen distal symmetrical, autonomic and cardiac neuropathy in the patient with diabetes. Diabetes, Obesity and Metabolism. 2022;24(8):1423-8.
Mumtaz H, Ghafoor B, Saghir H, Tariq M, Dahar K, Ali SH, et al. Association of Vitamin B12 deficiency with long-term PPIs use: A cohort study. Ann Med Surg (Lond). 2022;82:104762.
Gasmi A, Bjørklund G, Mujawdiya PK, Semenova Y, Peana M, Dosa A, et al. Micronutrients deficiences in patients after bariatric surgery. Eur J Nutr. 2022;61(1):55-67.
Bando T, Tokuda M, Katsuda I, Emi N, Tomita A. Involvement of folate and vitamin B12 deficiency in patients with normocytic anemia. Fujita Med J. 2023;9(2):134-41.
Downloads
-
Vistas(Views): 148
- PDF (Español (España)) Descargas(Downloads): 35
Published
How to Cite
Issue
Section
License
Cesión de derechos y tratamiento de datos
La aceptación de un artículo para su publicación en la Revista Médica de Risaralda implica la cesión de los derechos de impresión y reproducción, por cualquier forma y medio, del autor a favor de Facultad de Ciencias de la Salud de la Universidad Tecnológica de Pereira. 1995-2018. Todos los derechos reservados ®
por parte de los autores para obtener el permiso de reproducción de sus contribuciones. La reproducción total o parcial de los trabajos aparecidos en la Revista Médica de Risaralda, debe hacerse citando la procedencia, en caso contrario, se viola los derechos reservados.
Asimismo, se entiende que los conceptos y opiniones expresados en cada trabajo son de la exclusiva responsabilidad del autor, sin responsabilizarse ni solidarizarse, necesariamente, ni la redacción, ni la editorial.
Es responsabilidad de los autores poder proporcionar a los lectores interesados copias de los datos en bruto, manuales de procedimiento, puntuaciones y, en general, material experimental relevante.
Asimismo, la Dirección de la revista garantiza el adecuado tratamiento de los datos de carácter personal